For systematic-review teams

From research papers to reviewed evidence.

Collect studies, extract structured data with AI, resolve reviewer disagreements, assess risk of bias, and build your synthesis in one workspace.

AI assists. Your team reviews and decides.
University of PennsylvaniaDeveloped within Penn Dental Medicine·Learn about the research →
Collect & configurePDF · RIS · DOI · PubMed · CT.govExtractAI-assisted, linked to the sourceReviewR1 and R2 agree · CR records 124AssessRoB 2 · parallel-group RCTsSynthesizepooled, or synthesized without pooling124sample_size124R1R2CRD1D2D3
Smith 2024/smith-2024.pdf/patient_population_form
Study 12 of 24 in your queueReview · R1Example data
‹›page 4 / 12
Smith et al. · Journal of Dental Research4
2. Methods
2.1 Participants and randomisation

We enrolled 124 patients aged 3–6 years from four community clinics and randomised them to 38% SDF or placebo varnish. Allocation was concealed using sequentially numbered opaque envelopes prepared by a statistician not involved in recruitment.

Children were eligible if they presented with at least one active carious lesion in a primary tooth.

FieldValue
Source evidenceVerbatim · p. 4
sample_size124

“We enrolled 124 patients aged 3–6 years from four community clinics and randomised them to 38% SDF or placebo varnish.”

smith-2024.pdf · page 4 · Methods 2.1
R1Checked · 14:02EditConfirm
Select a field. Its available source text, table, figure, or page context opens beside it.
Workflow
01Collect & configureBring in studies and define the review.
02ExtractStructure results with AI assistance.
03ReviewCheck entries and resolve disagreements.
04AssessWork through RoB 2 with evidence.
05SynthesizePool results or synthesize without pooling.
Review and consensus

Independent reviews. One recorded decision.

Reviewers enter values independently. Where they differ, the adjudicator sees every entry with its evidence, a majority suggestion when two agree, and records one decision.

Consensus · Smith 2024
24 fields · 18 agreed · 3 resolved · 3 need decision · adjudicator CR
Example data
sample_size124AI · R1 · R2 matchAgreed
follow_up_months
Months from randomisation to the primary outcome · number
Needs decision
AI + R1 agree (2/3) · 12
Or pick a source box above, orEnter a different answerQuotes open the PDF pane at the cited page.
caries_arrest_pct68.4 · 68.4 · 71.0Needs decision
Risk of Bias · Smith 2024RoB 2 · parallel-group RCTExample data
DomainR1R2Consensus
D1 · Randomization process
D2 · Deviations from intervention
D3 · Missing outcome data
D4 · Measurement of the outcome
D5 · Selection of reported result
Overall
“Secondary outcomes were analysed post hoc”D5 · R2 · p. 9
LowSome concernsHighPending
Risk of bias

Assess risk of bias with the evidence in view.

Reviewers work through RoB 2 domains for parallel-group randomized trials with the supporting evidence visible, and resolve differences into a recorded assessment.

Synthesis

Reviewed evidence becomes synthesis.

Map fields to outcomes and comparisons, confirm eligible studies, then pool with a forest plot and diagnostics, or synthesize without pooling when pooling is not appropriate.

1 · Reviewed evidence5 studies
Smith 2024
48/62 · 30/60 · consensus
Eligible
Johnson 2023
70/95 · 44/92 · consensus
Eligible
Chen 2023
22/40 · 18/41 · NaF comparator
Excluded
Patel 2025
55/80 · 35/78 · consensus
Eligible
Okafor 2022
15/30 · 12/31 · figure-verified
Eligible
2 · Eligibility and mapping
caries_arrest → events · sample_size → N
Comparison: SDF 38% vs placebo
Chen 2023 excluded — comparator is NaF, not placebo
Okafor 2022 events read from Figure 2, reviewer-verified
3 · SynthesisMap fieldsChoose comparison3Plot4Diagnostics
Example data
Outcome
Caries arrest at 12 monthsSDF 38% vs placebo · Risk ratio · random effects (DL)Export CSVSVG
StudySDF n/NPlac. n/NRR [95% CI]Weight
Smith 202448/6230/60
1.55 [1.16, 2.06]27.6%
Johnson 202370/9544/92
1.54 [1.21, 1.97]37.8%
Patel 202555/8035/78
1.53 [1.15, 2.04]27.6%
Okafor 202215/3012/31
1.29 [0.73, 2.28]7.0%
Total (95% CI)188/267121/261
1.52 [1.31, 1.77]100%
0.5124← favours placebofavours SDF →
τ² = 0.00 · Q = 0.34, df = 3 (p = 0.95) · I² = 0%Low heterogeneityZ = 5.46 (p < 0.001)
Team coordination

One workspace for the review team.

Project owners define the scope and assign reviewer seats. Each reviewer sees the studies waiting on them; leads see progress across extraction, consensus and appraisal.

SDF
Silver diamine fluoride review
48 studies · 3 reviewer seats · owner: project lead
OverviewDocumentsFormsConsensusRisk of BiasSynthesisExample data
Collect48/48
Extract44/48
Review31/48
Assess18/48
Synthesize—
Review scopeEdit
P
Children 3–6 with active caries
I
Silver diamine fluoride 38%
C
Placebo varnish
O
Caries arrest at 12 months
patient_population_form24 fields · RoB 2 enabled
AssignmentsManage seats
R1Reviewer 1extraction · RoB 2 · 24 studies
R2Reviewer 2extraction · RoB 2 · 24 studies
CRConsensus revieweradjudication · all fields
Two independent extractions per study; one adjudicator records decisions.
My queue · R13 waiting
Chen 2023Manual extractOpen →
Patel 2025RoB 2 · D3–D5Open →
Okafor 2022Verify figureOpen →
Only the studies assigned to you, in the order they were queued.
JobsLast run 14:12
Extraction · batch 316/16Done
Extraction · batch 414/162 failed
RoB 2 · signalling questions18/48Running
Failed items keep their inputs and can be retried in place.Retry 2
Inputs and outputs

Bring evidence in. Take reviewed work out.

Records arrive from the sources review teams already use. What leaves carries the review with it: values with their source pages, judgements with their evidence, and plots with the study-level data behind them.

InDocuments
PDFFull-text papers · upload or drag in
RISReference libraries · RIS and EndNote
DOIIdentifiers · resolved to records
DBSearch · PubMed, ClinicalTrials.gov
Silver diamine fluoride review48 studies
  1. Collect & configure48/48
  2. Extract44/48
  3. Review31/48
  4. Assess · RoB 218/48
  5. Synthesize—
Everything below is produced from this one project.
OutExport
Extraction results
Every field per study, with source page and quote columns when you want them
CSVJSON
Risk-of-bias table
Domain judgements for each study, plus a per-study report
CSVReport
Forest plot and study data
Publication-ready figure with the study-level table behind it
SVGPNGJPGCSV
Exports keep the link back to the reviewed record.

Questions teams ask first.

Where does AI fit into the review?
AI can assist with extraction and suggestions. Reviewers inspect the evidence and make the recorded decisions.
What can I import?
PDFs, RIS and EndNote files, DOIs, and records found through PubMed and ClinicalTrials.gov search.
Which risk-of-bias tool is supported?
RoB 2 for parallel-group randomized trials.
Do I have to pool studies?
No. When pooling is not appropriate, eviStreams can retain the reported results and their sources for structured synthesis without a pooled estimate.